VR's rig reminds m of his playing: cluttered, overly complex, ostentatious...
But as to on the floor/on the table, back in, oh, 1982, I built a horrendously coffin-like 'table' full of stomp boxes, up high so they were at hand height for twiddling. I don't remember all of 'em but I know I had a Big Muff Pi, 2 Memory Man Deluxes, and MXR phaser, and MXR flanger, and a Mutron II. The only thing on the floor was a Morley Vol/Wah and this really cool, ahead-of-its-time Boss effects switcher (serial). Can't remember what the damn thing was called, but it was analog, and really worked! All your stuff plugged into a unit, and it had this massive, robust pedal with buttons (silent!!!) for switching connected to that via a cable. Beat the hell out of it and it never failed! I've tried to find mention of it over the years, but never have.
The rig, which I regularly used around NYC even got a few compliments from people like Rhys Chatham and Richard Lloyd (of Television fame). I remember once at CBGBs, a tech for some band called his friends, Joey and Johnny Ramone over to look. They were really nice about it, but as you'd expect, it wasn't their cup of tea.
Of course compared to VR's rig, it was stone age - but sometimes it is fun to have a lot of twiddleable stuff within easy reach.
I no longer do - just the Axe II and a PCM-70 for me, both in the rack, and a Dunlop vol/wah (soon to be replaced with exp pedal), Liquid foot, and Boomerang III on the floor.
And that's plenty complicated enough for this old geezer who is much less of a tweak-a-holic then he was back in the day.
Seems like a logistical nightmare to me, with all that stuff on a table and on the floor, using multiple controllers (floor, iPad, etc.), running multiple software programs etc.
But clearly he knows how to manage it, so more powerrrrr to him!
I don't think this could be handled by an Axe-Fx. Also because it seems he operates a lot of stuff in real-time.