Master Volume is my starting point for this stuff, depending on the amp anything over 2.5 starts getting mushy in the low end. If it’s a Mesa, you can pretty much drop the Bass all the way down and then add it back in with the 5-band Mark EQ. Pretty much everything I do for this stuff is using the Tone page and the EQ page of the amp block, I don’t really venture outside of that.
And just an example, this Fear Factory song is in A-standard and while there’s a gate on it, the gate is only set around 50%, it’s mostly right hand muting keeping things clean.