Hello all. I am going to offer a solution to everyone's problem using Axe FX as their soundcard, but it will not be a popular solution.
We all consider the purchase of the Axe FX 3 to be an investment, and I know there may be expectations based off the manufacturer claims, etc.; however, I am here to tell you that while the Axe FX 3 is a brilliant guitar processor, it does not seem to be performing well as a dedicated audio interface. It is a great additional feature, but it is not where Fractal Audio have spent the majority of their time in development.
This solution will cost 269.00 as of today at Sweetwater. Consider it the cost to get a 100% flawless setup with the Axe that works all the time, every time, whether software is running or not.
1. Go purchase a Focusrite 8i6 3rd generation. As I mentioned, they are currently 269 online. (this is the cheapest Focusrite (or any interface I think) that has SPDIF I/O)
2. Install the Focusrite software.
3. Buy two (2) SPDIF cables. You can order them cheap on Amazon. Usually any RCA cable rated at 75ohm will work.
4. Connect the Axe FX 3 to the in / out of the Focusrite with the SPDIF cables.
5. Set the Axe FX 3 to receive word clock externally in your setup.
6. Set the Focusrite 8i6 to default to 48khz (the only sample rate available for the Axe FX 3) and as master clock.
7. In the Focusrite control software, set the SPDIF inputs to be always active through your monitors. This software does not need to be running constantly....just for setup. It sets the configuration of I/O and allows audio passthrough like a mixer.
8. When recording: In your DAW software, set the Focusrite as the recording interface at whatever latency you prefer.
This is basically it.
You will have the ability to have the AXE FX 3 running audio (digital) into the Focusrite at all times, regardless of anything else going on: DAW software, Youtube, Axe Edit, whatever. You will always have a signal coming through your speakers / headphones / etc. I leave my Axe FX off until I need it. It boots up, and there is signal. Every time. No dropouts, no reboot, no fuss.
There will be ZERO delay during recording due to latency, because you will always be monitoring the AXE FX 3 signal DIRECT. You will set your track to record but not monitor the signal. Going in via SPDIF also means there is no D/A A/D before recording so the signal is as pristine as the internals of the Axe FX.
You will be able to record in the DAW of your choice (I currently use Logic) with very mature ASIO / Core Audio drivers (Focusrite have been improving the Scarlett range for the better part of a decade). Round trip latency is almost as good as RME on my 2012 Mac Mini.
You will get an additional 6 inputs / 4 outputs via the 8i6, including a couple of mic pre's. You will get 5 pin DIN MIDI I/O, and two headphone outs.
This is the most painless, straightforward setup I have ever had. No switching default drivers, no reset, no issues. I am 100% certain that this setup would work the same on PC as it does on Mac.
I know the appeal of just having the Axe FX 3 as the only interface / centerpiece of your workflow is desireable. It just is not there yet IMO.
Consider the 269 as an add-on to get the Axe FX 3 integrated.
I am sure there are other ways to skin this cat, but this one is the easiest I have found. I have been recording audio via computers since the early 90's. I am not new to this game, and have had more interfaces / computer setups over the years than I can keep track of.
This setup is dead simple and 100% functional.
When Fractal gets the Axe this reliable with the same level of latency performance and functionality, I will be happy to re-evaluate.
Best of luck to everyone!