For 1 example, I use the Solo 100 amp for 5 presets, set a little different in each. My main settings are Gain 6, bass 3.5, mid 6, treble 5, presence 3, master 5. I use a TS808 non mod, in front, with a gain of 1, tone 5, mix 100%, level 5.
With Beta 1, they were a little bass heavy, so I adjusted from 5 to below 3. Beta 2 perfect. Beta 3 cuts like a knife, very harsh.