I went through all my presets while on 16.01b then loaded 16.01 and, with my headphones on, my main preset sounded like it was out of phase or had a very wide stereo spread when I thought it was purely in mono.
So, I recorded a track to compare against 16.01b, downgraded the firmware, recorded a track in parallel to the first, chopped them both up, then alternately muted them so the sound would toggle back and forth. Hmm... nothing different.
So I reloaded 16.01 and restarted my test, and, again, no change in sound.
I decided I was tired and that 16.01 sounds great. ¯\(ツ)/¯