A lot of us record and have used the technique of recording two guitar parts ~exactly panned L / R, anyone come close to that sound on their AxeFxII?
For most of my cover tunes I am essentially doing this. It took a long time, been working them for months, but yeah...... Basically I double up and run 2 amps, and 2 cabs. For example, I did a tone match of "let there be rock," saved it as a cab. Then I make a preset and use a Marshall amp and that TM cab, and woohoo I got my go-to ACDC tone!!! but it's too thin for a live band, as is with most studio tone matches
so....... I then add a amp2 and cab2 and use different amp (I'm loving the Buttery ATM) and my own cab IR, and tweak and blend until it works live with the band, while still maintaining the basis of that ACDC tone.
We run a stereo PA and FOH so all my presets are stereo and panning depends more on the song, but for most i'm hard panned. It works good, but in a 2 guitar player band, this approach requires less gain on both amps, and you still need to respect and not pig all the frequencies so you can't be stubborn about your tone/sound if you want the whole band to sound good. This is the interesting part, because I've dialed in to our live mix so well, the preset on it's own sounds almost goofy and obnoxious when you first hear it, if you hear it alone, but....when played with the band, it fills in the gaps and blends perfectly, and makes us sound huge.
Another approach I use for solos is a virtual Wet Dry Wet load out. Using again 2 amps and 2 stereo cabs, I'll hardpan one IR from each cab, and then center, blend and mix the other 2 IR's. I then use effects and post process separately each signal, usually keeping the center dry, it works pretty good. You can get pretty crazy with the effects and controllers too if so inclined. I made a really cool one for when we play The Zoo that auto pans and delays while formant filters the low vowels and center has Wah on it.
The real trick is to not over do it, which can happen really quick when you double or triple it up.
BTW.... I also tried the Enhancer, and it just doesn't do it for me after doing dual amps/cabs.