I think, it's possible to get a much better sound from the AXE. A great affect has the cab sim, don't know, what cabs was used here.
Seemed like scooped mids on the Line 6.
Here he uses the 4x12 German stock cabOla usually uses his own IRs.
Here he uses the 4x12 German stock cab
I tried his presets and actually had to add a little presence for my taste. But I use a six strings tuned in Eb, he uses a 7 strings tuned to low A