Yeah the noise is exactly the same with headphones and the monitors off. So I am thinking that it must be the guitars picking up something. I don't have any guitars with humbuckers, just active EMG's and some weird pickup from Chapman guitars. I can use the gate to get rid of most of it on a distorted tone, but the cleans are killing me as you hear the noise just behind the notes and if a note sustains it just eventually turns to noise.
I also tried using a VST plugin called Brusfri that works pretty good. It gets rid of the noise but does steal a little brightness from tone. At a minimum that can be used to clean up some of the noise with the cleans. I have an old Les Paul in the closet that I might try and resurrect and do a shielding experiment and swap out the pickups for humbuckers. I will upload a clip of what I am dealing with when I get a minute. I am pretty new to all this so I am learning a lot from everyone here.