I can't speak to anyone else's opinion or perspective but I can relay my experience.
I spent 30 years using only tube amp's, one decade collecting vintage tube amps, and another seven or so years cycling through a wide array of boutique tube amps. I only kept as many as I was able to play through on a regular basis (I only keep things that I use).
I bought my first AxeFX (Ultra) at firmware v11.0. I had been following the AxeFX with great interest but the sound clips preceding the v11.0 release were impressive enough to me that I bought an Ultra within days of hearing those first few demo clips. Though I could clearly hear the difference between the AxeFX and my amps the gap was narrow enough that I lost interest almost immediately in all that accompanies the 'real thing' (varying wall voltage affecting the amps tone, their weight and size, the inconvenience of tubes going microphones at inopportune moments, the inconvenience and/or futility of trying to recreate the recording conditions of a track recorded during a prior session making changes / punch-ins / etc. difficult after said session, etc, etc...).
In fact I very quickly changed my perspective on what 'the real thing' means. In other words, the AxeFX Ultra took no time at all becoming the real thing for me. I put all of my amps up for sale within days of receiving my Ultra in 2010 and have never second guessed that decision (actually, I held on to an inexpensive tube combo for guests to use but it sat unused and I sold it after a while as it was only taking up space. Tube amp's still held a slight edge in tone when playing solo but in recording in playing with a live ensemble the subtle differences between an amp and the AxeFX were too subtle for me to give it thought.
I traded up to the AxeFX II at firmware v5.00 - that's when I heard enough of a difference for me to justify the cost. I have to say I'm constantly, pleasantly surprised when a new firmware brings the AxeFX II still closer to the amps being modeled. If development stopped today I would be no less satisfied. Yet development continues and the very small gap keeps getting smaller with every new firmware version. I no longer compare the AxeFX II to the modeled amps. Rather I find myself comparing the 'real' tube amp to the modeler as occasions to play through a tube amp arise and the AxeFX consistently compares favorably against what many call 'the real thing'. I can think of no sound reason why I would ever choose a tube amp over the AxeFX II.
How does the AxeFX II compare to the tube amps modeled therein? The answer at this point is: I personally don't care. The AxeFX II is the yardstick for me and amps are a poor substitute. As for the experience of others? A non-fiction for me as it only matters to me what I think, how I perceive it.
That's my $0.02