Well, I have been playing for 45 years, and I have had them all: Marshalls, Matchless, Fuchs, Fender, Carr, Bogner. Then I sold them all - well almost. I still kept a pair of Tech 21 Trademark 60's (amazing tone if you work 'em right - compressor and mild boost and EQ in front; good reverb/delay in the effects loop), a couple of Tech 21 PE-60's (powered 1x12 cabs), and a Fender Hot Rod DeVille, oh and a Tech 21 Bronzewood acoustic amp for my nylon strings.
One thing I have always hated about regular amps is that they are typically a one-trick pony (but it's usually a very good trick). Not enough tweakability though, and certainly not enough tonal range. I used to carry two racks, a Marshall 800 #2210, and two other preamps (Triaxis and Digitech 2101). The Digitech got me used to the idea of tweakable tones, great effects, and flexible routing. I feel right at home on the Axe FX II, except that I haven't sussed out all of the parameters, especially in the amp blocks.
I _did_ keep a Marshall 1960a just in case - I could always buy a head in a hurry if I needed one. Also, I have been wanting to try it with the Axe FX II, but I have limited access to power amps these days. Also, I would hate to give up the power amp modeling and the speaker modeling of the Axe FX II. Luckily I don't have to model the 1960a - I cheated and bought the Ownhammer IR that had a Marshall cab with GT75's through a SM57. Sounds good!
I will need to pickup some other FRFR's someday. For the moment, I am very happy with the two Tech 21 PE-60's.
Pete