Of course, happy to help!
Begin with standard I/Os. Add amp and cab block. Select Triple Crest 2 from the amp library. Select 2x12 RECTO V60 57 and 2x12 RECTO V60 121 from the cab library. I utilize low cut/ hi cut at 120 Hz/8500 Hz. Here are my reverb / delay settings that add just a touch of both to my clean and pushed scenes. I also utilize a Filter block that imitates the John Mayer QTron effect he uses on some of his songs. Also a drive, a wah, and formant. Note that Scene 4 Filter uses the first clean amp block setting.
Scene 1 Amp Block
Scene 2 Delay Block
Scene 2 Reverb Block
Scene 3 Amp (Pushed) Block
Scene 3 Drive Block
Scene 4 QTron Filter Block
Scene 4 QTron Filter Modifier
All Scenes Wah Block
All Scenes Formant Block
All Scenes Wah / Formant Modifiers