Trust your ears.
The people unhappy with something (anything) need to trust their ears. No matter what the GUI says, no matter what you "think" something needs to be in order to sound a certain way; cut through the complexity by simply trusting your ears.
How? Try something, turn it way up to hear what it does to the extreme. Roll it back till it sounds/feels good. Then check it on/off to see if it is better or worse. When you stop getting things 'better' then you are done. Then stop, play and don't look back. When given new tools, try them, do the 'better or worse' and then play. Stop tweaking, stop messing around and just play. If something inspires you; stop and play.
As for the whole 'live' vs. 'studio' preset concept, that's never held any water for me. Things either sound/feel good and inspire you; or they don't. Period. Good tone is good tone and can be used anywhere. Running direct-to-FOH means you have the *same* inspiring killer tones at the touch a toe. Done.
Seek simplicity out of complexity. Trust your ears. Stop tweaking. Play. That's my entire way of approaching this box. It has served me very well for nearly 8 years running.