A good IR will take you places. That was the reason I got into the IR thing in the first place in the Axe-Fx Standard days. I realized nothing else mattered as much as the IR.I use Helix Native but thought it sounded bad but I wasn't having much luck using my Axe-Fx II, Waves PRS and GTR or BIAS and everything sounded muddy until I got the Axe-Fx III. The Axe-Fx III has the tones I've been searching for but then I watched a video of @ML SOUND LAB comparing the Axe-Fx II and III using the same IR and they sounded almost identical. I then tried re-amping the Helix Native w/o a cab into the Axe-Fx III with only a Cab block and it sounded exponentially better.