I'll add a little more to the mix, no pun intended, in the hopes it helps someone else. I didn't care much for either the Sony MDR-7506 or Audio Technica MTH-40x that we had laying around the house. So I took a chance with the new Sennheiser HD 560S and not only did they sound sound much better than the Sonys or the ATs they are much more comfortable as well. I know they're marketed as consumer oriented "audiophile" cans, but I like what I hear.
Agreed about the Sony headphones. Very limited in the lower mids. No girth to the sound. Narrow sound stage. Unpleasant high end. Quite boxy for me.