Understood. So you're running SPDIF to and from the interface? Does that allow re-amping? Currently I'm only running SPDIF from the axe to the interface but nothing back from the interface to the axe.Technically, yeah. This setup works for me though as I can use all of the other inputs of my interface without changing around my audio device settings. Gives me a bit more flexibility as the AxeFX is just another piece of my studio rather than the central interface (for example, I can jam on a guitar plugin without powering up the Axe if I want).