What is possible with 2 AXE IIs?

I would use one for my regular stage rig w real power amp, cab & lots of gain and the 2nd for ir cabs & going direct w about 5/8th of gain.
 
My first thought was this:

One rig into a tube power amp and cab on stage with cab and power amp sims off
One rig mirroring this but with cab and power amp sims on straight to FOH

Second thought, complete redundancy (as in a backup unit)
 
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