Well I guess I'm having fun with the Friedman tonight. Your Bogner mix 01 provided good results with it. But my favorite so far with the Friedman's have been a mix of your G20M 57 and 121 for that amp. I can't remember which ones by memory though.Those are my go-to Mesa mixes as well.
The IIC++ is probably my favorite Mark series model at the moment, so I feel you there.
As far as the HBE 2018 C45 goes, I have a few subtle tweaks you can play with. First, I set the Gain Enhancer to 1. It doesn’t need much, but that little bit helps the feel IMO. Next, Friedman amps can be a little muddy in the low mids, so I like using the Output Graphic EQ and cutting about 1 dB of 250 Hz. You can go deeper, but I find that minimal cuts or boosts give you a more natural result.
When the EQ feels good, I’ll tweak the gain. Depending on the guitar, I lower the input drive or drop the input trim to about .7 or .8. to clean up the distortion texture a tad.
Lastly, some guys hate top end air and some guys love it. If you like air and aren’t getting it with the Friedman models, go to the preamp page and bring up the preamp high cut. I like it anywhere from 10k-16k if I’m going for a Marshall JCM 2000 DSL 100 thing.
BYW, you forgot the most important part! Which IR/s you liked most with the Friedman!