Well you've the DI speaker thru box already sorted very nicely it seems - so if you follow the set up steps in the wiki article (starting at "
How to perform Amp Matching" section) here:
https://wiki.fractalaudio.com/axefx2/index.php?title=Tone_Match_block
Your 'local AxeFX amp' will be the Tube Pre with all values at noon - which at those settings is supposed to be the equivalent of a neutral tube power amp
You then need to scroll down a bit to the bit where it says "When using a power soak" - as you're using a attenuated down DI taken between the 295 and speakers rather than a mic pre and mic in front of speakers.
If it works at all then your Tube Pre amp block and resulting TM together 'might' constitute a match of the 295 ... so bung your CAE3 into rear Input 1(s) - your Chorus into the AxeFX FX loop returns and treat the Tube Pre + TM blocks as the power amp 'model' and stick your preferred Cab IR after it somewhere
........ if it doesn't work just remember I live in the deepest darkest countryside far far away and you'll waste even more time than the Amp Matching attempt took trying to find me.