Squealing Sound

Ok I just started playing with my new Axe FX III. Every high gain preset has a high pitched squealing whistle something in the preset and its not my amp or speakers as I ran straight into headphones and hear the same damn thing

Can you show a screenshot of AXE Edit rig please?
I think you are using you tube amp, where do you connect the AXE output?
Can you describe the signal path?
thanks
 
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