I don't know why people are not going for the 15s. A 15 pushes more air, and will get you closer to the thump of a 4x12. The trade off is a recessed midrange, and a bigger footprint, but I think its worth it. I personally own some 12 coax wedges however I can not stop thinking about how amazing the 15s I tried were.
For me, the magic is in the mids. I've never been able to say I was happy with guitar tones out of 15" based PA mains.... I prefer 12" with subs for mids (guitars/keys/vocals) that work for me. IMHO, no different with monitor wedges.