For you maybe.
Are you using 4 ohm cabs btw?
For me, I'd be using 8 ohm cabs which gets the Mosvalve's power down to around 40 or 50 watts per side.
For the types of clean jazz playing I tend to do, which needs surprisingly high headroom in a power amp, that simply wouldn't be enough power and I'd be noticeably lipping the Mosvalve.
I owned one of the original Mosvalve power amps when they first came out.
Used it with an ADA MP-1.
It was a nice rig for the time.
Circa 1986.
Sure, the Mosvalve needs to be driven quite hard before it will noticeably break up but you need to be aware that it distorts the signal well before you get loud enough for it to be noticeable.
That's why/how it feels more like a tube power amp.
With the Axe, technically speaking, it's best to have all the noticeable power amp breakup (and/or any more subtle distortion of the preamp signal like power tube compression, etc.) happen within the Axe's power amp sim.
The more headroom from your physical power amp the better it will be at reproducing what the axe is actually putting out w/o distorting its characteristics.
But you should also consider that when your physical power amp does distort the signal it's not just the guitar amp sims that will be affected.
The signal generated by the Axe's Reverbs, Delays and Choruses will also be distorted compared to the the pristine quality that they'd have with a power amp that has more headroom.
Of course if you're getting a tone you like to play with then that's all that counts.