I've just made a standard practice of Low Cutting my Cabinet block at 85 and Hi Cutting it at 6500. I have not gone down as low as 5000 though.....although I am sure that it is perfectly fine around that range as well. Most guitars are going to sit in that 85-1500 range fundamentally, but the overtones will go up to 6000 or so, as well as going down below 85. However, when the sound engineer gets a hold of your signal at the board, they will most likely cut you around 100 to leave room for the bass and kick, and will most likely cut you about 4500-5000 to get rid of that harshness and leave room for the keys. cymbals, and airiness to vocals. SO..... I would guess doing a cut at 75 and 5000 in your cabinet block will be just fine and send them the signal they want. The question though is....where is your cabinet block in your signal chain? Is it the very last thing before it goes out of the magic black box? Or do you have delays, reverbs, modulation, etc... after it? I have always been of the mindset that if its not last in the chain(like it would be in an analog rig setup) then it is just controlling what you feed the effects after it. There can always be regeneration of those frequencies you are trying to cut in the cab block by those effects that are after the cab. They can regenerate those overtones based on where you put your lo and hi cuts on those effects. I hope that all made sense.......just something to think about. I don't claim to be a sound genius so I could be wrong about all this, just sharing thoughts and ideas I have had.