I'm a long time Mesa power amp user, I had a 50/50 and then switched to a new 2:90 and yea, the sound and crashing power is there!
I also go 2 friends with a same setup as yours, running a 395 with an Ultra.
So yes, the sound and volume is there but also the weight and $$$ to re-tube (8 x 6L6) and above all, caring around when rehearsing and gigging was giving me a heart attack each time dew to weight and fearing a tube will break or something.
I ended up selling it and buying a Matrix GT1000FX, I can say it is not 100% identical BUT it is as good in terms of sound and power and its light as feather, its solid and reliable and it has 0$ maintenance and yea, it covers my 2 setups, FRFR and traditional cabs.
If you are playing only @ home than yes, go for it. Also your tubes will last forever, I had my 2:90 running for something like 3 years on the same tubes when it was @ home only (low volume = low maintenance).
If I had the $$$ and I wanted a "nonmoving rig" which stays @ my studio 24/7 than I would have probably keep the 2:90 as well but as mentioned I'm gigging and playing outside my studio so mobility and $$$ is an important factor for me.