From what I've experienced so far, if you want to take full advantage of the Axe FX2 power amp modeling, you should avoid any tube base power amp in your signal chain. I have both an Atomic active cabinet and a Matrix Gt800FX. Believe me, they sound absolutely different feeding the Axe fx2. With the Atomic, I was always struggling with the ridiculous over amount of unpleasing highs in my tone. I was setting the tweater in the neutral position and power amp sim in the Axe was on. Obviously, the Atomic is far from being a neutral amp, and there was nothing wrong with it since I had 2 of them and both sounds the same. Then, I bought the Matrix. I run the output of the Matrix to the external amp input of the Atomic to bypass it's internal amp, but I still can benefit from it's neutral speaker and cab for the Axe FX2 cab simulations. And guess what?? WWWOOOOWWWWW!!! A whole different story here with the Matrix. I now hear the Axe fx, not the Axe fx going thru a colored poweramp. The Atomic might be a good option for those who bypass the power amp modeling of the Axe ( What's the point?). But if like me, you want to benefit from all the magic inside the box, then the Matrix is one hell of an option. It's really transparent. No, there are no tubes inside and that's a good thing because the Axe fx is so much sounding and feeling like a tube amp, that pairing it with a tube amp is like plugging the output of a Marshall Plexi in the input of a Mesa tube poweramp!!! Poweramps, whether tube or solidstate, shoud not color your tone, it's suppose to amplify your preamp without changing the tonal character, unless that's what you are after. But you can't go wrong with the Matrix!!