I know the manual is indicated as being version 4.10beta, which is odd. The LF software is up to v 4.31, and I'm running that version on my LF+JR+. It took me a little time to understand how the LF+ system maps to the AxeFX, but after some experimentation (and careful note-taking) I have it all working pretty well. It's amazing to me how powerful the LF+ software can be, and once I got my basic programming worked out, it started to really click for me. The MFC has awesome plug-and-play integration with the AxeFX, and it's a fantastic controller. I just wanted to reduce size / weight for touring, and have started to really love the deeper functionality of the LF+, especially the use of Pages and IA / Preset Steps.
I am not an expert, but would be happy to help if anyone is having trouble getting set up. The manual helps, but it doesn't accurately map to the current software, so it can be a little confusing.