Amps are incredibly loud. LOL. Yes, I can mic my cab, but my music space operates mostly as a mixing area. I don't have a separate treated room to put a cab in, and my dog would hate me for it anyway. Also, with the great impulse responses available in this day and age (long gone are the redwirez days) I can get AWESOME tones direct anyhow.
In all seriousness, I tried out a Two Notes Torpedo with a 5150 iii 50 watt roughly 2 years ago. I don't know if I had a bum unit or something, because after 3 days of use it just didn't turn on.
Before the total failure I noticed that if I turned the amp up much past 9 o clock there was a pretty significant loss of detail in both the highs and the lows of my signal - particularly on high gain patches. I could tell there was a richness in the signal compared to the Axe-fx II, but the limitations imposed by this particular problem gave me pause. When it didn't turn on the 3rd day, I just said screw it and went back to the Axe.
When I bought this amp this time, it was for the exclusive purpose of running the test again with the Fryette, and if it didn't work out a buddy of mine was going to buy the amp (provided it didn't have the "suck-a-tude"). The Fryette doesn't seem to have this problem at all, as at one point during my testing I had the amp turned up to around noon and I didn't notice the behavior. In fact, it seems to retain the qualities of the amp QUITE well. Surprisingly so.
As far as IRs go, I hadn't been using the cab block in the Axe for a while anyway. I have been loading IRs through MixIR2 (or any other IR loader for that matter - I just didn't use Cab-Lab because I had problems with it crashing Logic in conjunction with some plugs I used) and was much happier with both the sound and the flexibility of the practice. It's been my long-standing (albeit somewhat unpopular) observation that I got better definition my way, and it works out fine with workflow. CPU hit is so low on modern machines I don't even notice it.
Simply put, yes, I personally liked the sound of the real amp through IRs better than the modeled sounds through IRs I was getting out of the Axe. But these things are all subjective.