hese kinds of "scientific" comparisons are a timesuck and not worth the squeeze ime.
Its work to do, but worth it for those that truly want an answer as to why their tone doesn't match someone else's when played thru the same preset on their instance of the same modeller. I wouldn't call it scientific - more like having LT come to your house (via DI + preset) and play thru your Axefx - if it's the same, you have your answer (guitar / hands) - if it's not the same, you have a direction to follow (re-confirm no post processing on the reference tone, confirm you are re=amping correctly, check fw, methodically check globals, last resort: check for hw problems). What's not worth it, imo is the endless shots in the dark without any plan of attack for resolution and without any resulting definitive answer like often seen in "why don't I sound like xyz" threads.
What's most amazing to me is that often, not in this thread, but often, we have posts immediately assuming Axfx is problematic wrt getting a target reference tone when the guitar is clearly not the same (or we embark on discussing possibilities without even confirming wha the guitar is). Guitar makes a huuuge difference - I am reminded of it today as I try to get a good sound out of a PRS style guitar I recently bought which sounds like total dog doo compared to very similar guitars I own (similar pups, same scale length, same wood ...) thru the same preset - so much different that I had to record DIs for both of them and A/B them back and forth thru the preset to prove to myself that, yup, this latest guitar I bought, tho very similar to others I own, sounds like shit compared to those other guitars thru the same preset - it's not a gear problem. Being methodical ("scientific" if you will) helps avoid going round and round.
Some of the drudgery in doing this could be for the tone superstars here (CC, LT, Burgs...) to perhaps regularly (maybe after major FW releases) post sample packages including Output Clip with matching DI + Preset. Of course they'd need some sort of compensation for this as it's pretty dry stuff that doesn't likely generate any clicks for them - maybe thru their patreon subscriptions - something like that.