I'm finding some ways to tame it quite a bit. I don't know what options the OP has in a II (I never owned one) but here's what I'm doing in the III-
-Parametric EQ after the Cab, Frequency 5 set to Blocking, the Frequency is around 6611.0HZ (Wiggle that knob around, there's a lot of it in here), 18 db/oct
Tonestack- This REALLY helped tweak it. I changed Tonestacks, messed with the frequency. I'd just play around and see how it works for you, there's a lot of wiggle room in there.
HiCut Frequency in the Preamp section of the Amp block, I dropped it to 3390 Hz.
The less gain, the less fizzy sound. I also added a 2nd cab and just kept scrolling through different ones. Some types of blended cabs seem to restrict the amount of annoying fizz coming out. It seems it's always going to be there, I think my focus needs to be on how to fine tune it so it's not overbearing. It's almost as if the frequencies in the distortion were all separated and mismatched, like the top end doesn't belong with the bottom end.
Honestly, I don't know how much of this stuff would even present itself in a mix and if it were, I'm getting 95% of the way there with the AxeFX, I don't mind getting that extra 5% from an SSL Channel strip plug-in and zeroing in on that frequency. I'm also going to play around with the settings on my monitors to see if I can attack it from that point.