Yes, the vintage reverb with diffusion at 100% is a definite improvement. I've been trying to recreate the Misirlou sound but haven't been able to get the bouncy attack on the lower strings. My Strat seems excessively bright with some unpleasant transients at the front of each note when hitting the strings hard. Dropping the Pres or Treb just makes the tone muddy. I've recently replaced the bridge pickup with a Lollar blackface so I reckon I should be able to get close. I'm using the Blackface amp model and I've twiddled all the parameters, (Drive, etc.) inc. the ones in the Advanced tab but I'm still not quite there. Cab is a 4x10 bass, but I've messed with the others too. That one seems to work best.
I've not got my MIDI setup sorted yet as I'm still deciding on the best form of amplification. I guess I'll post the preset to Axechange when I've got my MIDI hookup sorted.