I also run tube preamps in my rig along with the amp block as second channel on my non-turbo FM3, and I've not had any problems like you describe?
I have no reverb in my main live preset (it's a MXR Timmy/JCM 800 tube preamp/Tonex One for tube power amp sim plus FX), so if you do check there first, but I do have a compressor which I had to change from JFET studio to JFET pedal to reduce CPU. Otherwise, with regards to all the other blocks no change, though I did have some corruption of my foot-switch settings caused by attempting to edit them via the new editor, but I simply restored from backup and now I'm not editing them until this is fixed etc.
On my Blues/Jazz/Americana preset (it's a MXR Timmy/Twin Reverb tube preamp/Tonex One for tube power amp sim plus Drive and FX), I had to adjust the Large Spring Reverb down to the Medium Spring Reverb to get under CPU, but the spring reverbs are wonderfully improved along with the compressors, so well worth the effort.
Also note that the Cab Block's Room sim has had major changes, so check there as well if you're using it (I'm not using it).
Bonne Chance!