So - I have a Sapphire Pro 14 interface, which my Axe Fx is hooked up through via SPDIF, and the noise from my PSU seems to be coming through my monitors. It's like a scratchy crackling whiny noise - that gets words when I open new windows on the computer, scroll, etc. I've tried 1/4" connections as well, same thing. I've tried a different interface, same thing. (presonus) The only thing that makes a difference is hooking my monitors up straight to the AXE FX, but I need a setup with the Sapphire in it to record vocals, etc. All my power is plugged into one strip (and the light on the power strip says it's grounded). Any ideas??? This is really annoying. Like I mentioned - it's nearly un-noticeable if the monitors are connected right to the Axe Fx.
Chain --> Axe fx SPDIF out-->Sapphire Pro SPDIF In--> out to monitors
Chain --> Axe fx SPDIF out-->Sapphire Pro SPDIF In--> out to monitors