Sure you can. The TB200 is a full-on guitar head for those unaware, and it sounds pretty great. Just too bad it doesn't have an effects loop so you could 4CM, but pedals straight into the front of Fender combo amps was my bread and butter rig for well over a decade. TB200 makes a nice replacement for, say a 80 pound Twin.
I squeezed my TB200 onto my old pedalboard along with a comp, wah, 4 drive pedals and a Zoom cdr-70 at the end of the chain to take care of del\rev\mod, noisegate, and tuner. Signal chain goes right into the front of the TB.. it's a complete rig in roadcase not much bigger than a briefcase, I just grab one of my cabs, a speaker cable and my pedalboard. I'm already thinking of an FX8 to replace all those other pedals (and end up with a much smaller briefcase).