I suggest putting the names of all the amp models on a cork board. Get a dart, and a blindfold.
Any of them could work.
It's in the way that you use it.
Personally any plexi model, hbe, FAS brown, Brit brown for my definition of "lead".
I gravitate towards the British gain sound.
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Not enough information on the question.
• Genre?
•*Type of guitar?
• Searing 80s metal lead, or clanky indie rock lead?
I ask because I have more then one lead amp. I use the ENGL, Marshall 100, 5153 Red, and Vibroverbs with TS9s in front all depending on the song and the type of lead needed.