Well, as much sense as that LTI-talk might make to a engineer or a scientist, it doesn't make all that much sense to me!
I'll have to y'all's word on that.
For me, the question has always been; When do I want to run my sound through the filter of a guitar speaker?
Does it make more sense to lose those frequencies prior to reverberating them or after.
I've always thought that prior was more sophisticated because it models what goes on in a studio: Amp > Mic > Effects, especially if you're using a speaker that breaks up for a rock sound.
But, unless there's speaker break-up involved, it may not really matter where in the chain those frequencies get filtered out.
If they're filtered out pre-reverb, then they simply won't be present in the reverberated signal. If they're filtered out after the reverb then they won't be present in the reverberated signal either, possibly in the same proportions either way.
And I've noticed very little if any difference putting the cab sim at the end of the chain. I don't generally use speaker breakup very much though.