I use 1/4 inch to XLR adaptors to run Output 2 to my (XLR-only) monitors. There is some minimal signal degradation, a bit more noise, etc., but it's quite acceptable. It leaves my Output 2 XLRs free for sending the signal out to FOH. I can live with a touch of degradation for my personal monitoring, but I want the best signal out to FOH (and/or recording). You mean it leaves your Output 1 XLR's free for sending signal out to FOH , correct?
(EDIT: when I'm not routing anything else from Output 1, i.e. no PA, no recording, nothing, then I use the XLR Output 1 to drive my monitors... just as a treat, cause it sounds better and cleaner... but I easily give it up when I need to feed a PA or a recording console).