I think not. There are wish threads that ask to have amp/cab/power amp things turn-offable per output 1 or 2 separately, but that's not how it is designed currently.
It may seem like a lot of work, but that's only if you want to audition all the presets. Of course you'd have to add a Fx loop to each one, but how many actual presets will you use?
Set the global settings for FRFR or guitar cab, whatever you use right now, and audition everything. Pick your favorites and build your patches. I only have 5-10 and adding an fx loop to those 10 really wouldn't be too hard.
It may seem like a lot of work, but that's only if you want to audition all the presets. Of course you'd have to add a Fx loop to each one, but how many actual presets will you use?
Set the global settings for FRFR or guitar cab, whatever you use right now, and audition everything. Pick your favorites and build your patches. I only have 5-10 and adding an fx loop to those 10 really wouldn't be too hard.