When reading such comparisons, I tend to think that in order to really accurately compare any amp+cab, end to end with Axfx, one would first need to shoot an accurate IR of the real cab, measure the real cab's IC and have those values present in the Axfx model. Then with that, A/B audition both with the preamps set equally, and the power amp sections being pushed equally (and not just using knob positions to confirm that equalness since knob tolerances vary), and listening to the real amp+cab mic'd (with the same mic in the same room as was used to shoot the IR) through the same monitors as Axfx. Of all the real amp to Axfx comparison threads I've read here over the years I don't recall any that ever went through that kind of process to ensure no apples to oranges effect, which makes sense because it's a lot of work and requires some specialized gear (IC measurement). Comparing Axfx to real preamps is easy to do (and probably best done as a prerequisite to an end to end pre+p.a.+cab comparison, to ensure the preamps are equal in isolation to start), while comparing Axfx to real pre+p.a.+cab is a pretty tough go - and that's just to compare one static sound, never mind comparing Axfx vs real end to end in terms of response to controls variations or feel.