Very simplest way to my eye, is to have fx loop block into amp block with two scenes:
1. Clean, fx loop bypass'd and amp block engaged.
2. External Preamp, fx loop engaged and amp block bypassed.
That's it - see below:
Clean Scene
View attachment 113091
External Preamp Scene:
View attachment 113092
Connections:
- Guitar > Axfx In 1 front.
- Axfx Out3L > External Pre Input
- External Pre Output (ie External Amp Send) > Axfx In3L
- Axfx Out1L > External Power Amp (ie External Amp Return).
Global:
Input3 set to "Left Only".
Output3 set to "Sum L+R"
Preset attached - start with low output1 level in case of volume spike.
Refine loop level with Input3 Level knob.