I am very happy with my rig [FXII and MFC-101]. Just when I think it can't get any better, a new firmware release comes, and it gets better. I do not plan to make any changes to my stage rig or recording process. I never thought I'd say that, but thanks to FAS, I have the best tone I ever had. Thanks FAS!!!
As for guitars, I have a bunch. I have been collecting them for many decades now. I have never had a "favorite", as I tend to use the guitar that best serves the song. I guess I really can't say that anymore, as I have recently developed a great fondness for my Carvin DC-400. The more I play it, the more I like it, and the more I like it, the more I play it. It is extremely versatile, stays in great tune, and just sounds killer through my rig. I gig a lot, and a lot of guitarists will ask me about my gear after the gigs. The amp snobs are floored that I just use the Fractal, and the guitar snobs are floored that the pu's in the Carvin are stock. I don't use any standard presets for my tones, but did use a few to give me a great starting tone. Some I tweaked a lot, and some just a tad. Point being, I am not GASSING like I used to. Fractal is the best gear I ever bought. I just do not see myself making any changes to my rig. But I wholeheartedly agree with Sidivan about never ending guitar quest. I already have my eye on another DC-400 for a back up.