My acoustic setup is rather complicated as axe patches go. 2 pickups, D-tar wavelength and k&k pure western. both into input 2 L/R. the k&k gets minimal compression and eq, as it sounds pretty good as is. The wavelength gets a little eq and, more importantly, goes through an user cabinet IR of the d-tar mama bear preamp, which is one of those acoustic modeler preamps, similar to the fishman aura.
Sounds great and pretty realistic. I have several notch filters in the setup as it quite resonant and prone to feedback, however.
I need to get an acoustic simulator for electric guitar patch set up, though, I realized the other day.