Great topic, I'll be watching. I haven't swapped tone stacks yet. I got sucked into the IR vortex and spent a lot of time auditioning various cabinet IR's. I'm just using the stock IR's I haven't bought any cabinet packs yet.
Next I got sucked into the drive block vortex and have spent a lot of time auditioning various drive blocks.
I did fool around with moving the tone stacks to various locations and seeing how that effected the tone. Mostly I stay with the basic amp. When I had an analog rig it was just a good OD pedal (Kingsley Jester) Amp, Tremolo, Delay, Reverb and out.
So far my favorite amps in order are Black Face Twin, FAS Class-A, Divided by 13 CJ11, Mesa Lone Star, Dumble and Hook.
The Twin is just money. With a couple of drive blocks it can go anywhere.
I'm looking forward to seeing how you all are using the tone stack swap.