You could make your life way simpler if you run dual amp models, and effects, in the Axe, and just use an amp head as the power amp, one head for the right and one for the left channel.
4 cable method is tough enough with just a single amp, but trying to run dual 4CM, and then also control everything from the MFC is a complex setup.
If you have some idea of what your doing with routings, know how to program the MFC etc, it could likely be done with some help, but if your clueless with that stuff (no offense meant) you'd probably be better of paying someone who specializes in setting up a custom rig like that.
Given your level of understanding, its just not going to be practical to get it all up configured via some post on a forum. There is a ton of stuff you'd need to be taught before you could even get to the trickier stuff