Instead of the effects layout I use per-preset footswitches on my per-preset layouts (2 layouts, one for PP 1-6 and the other for PP 7-12. This way I can customize the footswitches on a per-preset basis i.e. I don't need to dedicate a global layout footswitch to phaser 1 if I only have phaser 1 on one preset.
The top 3 buttons for me are scenes, PP 1-6, and presets. I set those 3 up like that in all of the layouts. When I'm in the PP 1-6 layout that footswitch changes to select the layout that has PP 7-12 and vice versa. Hold function for the presets button in all layouts is tuner.