When I bought my AX8 at the end of last year, I figured the best way to learn how to program it would be to make song-specific presets for my weekly gig (a live karaoke band with nearly 300 songs on our song list). While I got the hang of building presets, after two weeks I found myself with over 60 of 'em - which quickly became totally unmanageable in a live karaoke format where we work without a song list and don't know what song we're playing until we're about to count it off.
I got my FM3/FC6 about three weeks ago, and I've set up six different presets - one for each band I either play steadily with or sub in with (3 rock bands, a country band, an R&B band and a Neil Diamond tribute band). Basically I set them up with 3 clean scenes with different effects and 3 'hot' scenes with different stages of gain, rhythm, hotter rhythm and solo. By switching to the effects layout I can apply a boost or null filter (or both) to the clean scenes to kind of fill in the blanks between the clean and higher gain scenes for solos, and momentarily use a different effect on whichever scene I'm in. I use the same IR on each preset so I don't drive the poor sound guy crazy, and I love the '65 Bassguy Normal for clean tones. I use either the Marshall or Soldano models for the hotter tones.
I have two Fractal EV1 pedals on my board. I use one strictly as a volume pedal so I can lean into certain parts and pull back in verses, and the other as a wah/whammy or to control the rate of the rotary effect. I'm only scratching the surface of using the second expression pedal, and I figure I'll get more into that as I learn more about the FM3.
Having worked with the AX8's X/Y setup for amps and effects really helps me appreciate the FM3's 4 channel setup, and using OMG9 gives me a ton of switching mobility, which is really nice to have in a live situation. And using one preset per band is a whole lot easier to manage, and I find I can get in the neighborhood of an appropriate tone for whatever song I happen to be playing, and whatever band I happen to be gigging with.