One other thing, and this is purely subjective, about FRFR. The whole point of the FRFR thing is to *really really* sound like totally different amps when you switch patches. That's cool for recording and getting great sounds at home. But live, there is a bit of a complication that I've found.
I used a rack with a triaxis, mesa power amp, and a bunch of effects for many years. Even though I had tones ranging from very clean to very overdriven, no matter how drastically different my sounds and EQ curves were there was a basic footprint that was consistent, in part due to the common power amp, same cab, and of course it was all the same preamp. That consistency goes away when something models as well as the axe. You may love the sound of an AC30 with an open back 1-12 cab, and switching to a marshall thru a 4x12 for crunch and a Diezel or whatever for lead, but those amps, especially considering the different speaker cabs, have very different sonic footprints. I found that switching between such drastically different amps within the same song created these weird disconnects in terms of the space within the sound spectrum I was taking up. I mostly play 3-piece so that really messed with my mix; I try to fill a lot of space and I think it's important to fill the *same* space as the song moves along.
I think that guys like Eric Johnson and Joe Bonamassa who use multi-amp rigs have mighty soundguys compensating to some degree for the differences between the amps. But when you are going direct you can't hide the difference in footprint between a supro with an 8" speaker and a Rivera with a Los Lobottom sub (for an extreme example). So what I've done with my live patches is try to use consistent speaker emulations for different patches, and mess with the power amp parameters so that the sounds take up similar sonic space even if they are dramatically different. For example, I use a recto cab right now, and a recto cab sim in my feed for almost all my patches no matter what amp they are based on. As odd as it is to play a twin or a Dr. Z or a marshall all thru a recto cab, it helps my footprint stay consistent (and that's what's sitting behind me on the stage so it's easier to match my stage tone with what's out front more consistently). I also tweak some of the power amp parameters to try to massage the tones into the same footprint since different amps take up different space even regardless of speakers. I've made some exceptions, some sounds just demand a certain speaker type. You can mess with it a bit without creating the weirdness I'm talking about, but you really need to be careful mixing and matching small and large amps in the same song.
I don't know if that makes any sense to you, but it's one more reason that I don't go full-range ontstage. I use a lot of different sounds and effects from spanky clean with compression all the way to super saturated, but I try to take up the same space with each one. (I'd be a better engineer than guitar player.... too bad my hands aren't as good as my ears :mrgreen: ).