That are my observations, too. Haven't been near my Axe-Fx II during the last weekend so I could do no further testing. But building a dedicated pulseaudio conf file for the Axe-Fx II and adding an appropriate entry to 90-pulseaudio.rules could possibly help. There are already some of such conf files (located: /usr/share/pulseaudio/alsa-mixer/profile-sets) for the M-Audio Fasttrack Pro and some Native Instruments devices. Maybe the file default.pa has to be modified by adding some lines to manually load module-alsa-sink and module-alsa-source with parameters for the Axe-Fx II. There seem to be at least some successful attempts on doing so to make RME and Terratec sound cards work.