A must have or must do on axe fx when making new tone?

i, too, tend to stick with a standard grid template.
standardgrid__zps4677ff8f.jpg

the only things that change are the amp and cab blocks for each preset/scene and occasionally the reverb block.
 
When playing user cabs and playing in mono, you can use Cab-Lab to mix the IRs into a single one, HiRes or UltraRes, and save precious CPU power.
 
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