I've never thought there was anything special about Guthrie's tone. The playing is a different story.
He used factory presets for the Late Nite Sessions 2 videos - USA Lead and Friedman HBE
I read somewhere that the presets were stock except the delay and reverb were bypassed, as these were added from the deskI remembre reading at the time that he was using the HBE stock preset with the presence pushed a bit.
Yes, they were stock factory presets. Only the delay and reverb levels were adjusted.