I run my Axe FX through a power amp into a regular speaker cabinet (orange 4x12 slant w/V30s). The manual suggests turning speaker cabinet simulations off when using this set-up. I transitioned from a POD where that option is not available, so I initially ignored this suggestion, but recently thought I should do the "right thing" and see if there was a difference. It seems that most settings sound better with the cabinet simulation on, but I can hear some nuances in the sound than could be fixed. Obviously, I want to do what sounds best (regardless of the manual) but I do understand that the frequencies will be different with a regular cab than a full range setup. Which finally brings me to my question. If I run with the cab simulation on and insert an EQ, are there any "magic/go to" frequencies that I can tweak to compensate for the regular speaker vs full range speaker sound difference? Any help with my clear as mud question would be appreciated.