the seymour duncan website has a "compare tone" page. They explain the guitars and amps used for each recording and the settings of the tone knobs. You can choose up to 4 pickups and quickly compare how they sound with clean or distortion settings. Fortunately for you, the reference guitars for humbuckers are Les Pauls. This should give you a fair assessment. I was there yesterday because I watched a rig rundown for Neal Schon and he was talking about his new semi-hollow PRS guitars, which will come with PRS pickups, however, he is using Duncan CUSTOM CUSTOM in his bridge. I thought it was interesting because he had been using DiMarzio in his Les Pauls over the past 10 years.
I guess he wanted to "start over" and make a clean break from Gibson and also wanted to start a fresh with another pickup source.
I have a Fernandes Monterey Elite, and it is the first guitar I've owned with a Duncan JB in it. I absolutely love the sound. The pickup out performs every other aspect of the guitar itself, I'm afraid. I found it very interesting that in my Fernandes, it comes across as much darker than the other guitars I own, but on the Duncan tone comparison site, the JB sounds brighter than the other 2 pickups I was comparing it to: Duncan Custom, and Custom Custom.
Now I'm more confused about what I should get for my Schecter Hellraiser when I remove the EMG's. It is a shredder guitar, but I am not a shredder, I do not need shredder type tones. I just want an all around good balanced sound, reminiscent of the JB or Custom Custom, but it will depend on how it interacts with the guitar body itself.
I love this process (never ending tone-quest), but it does make my head hurt sometimes....